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Related Experiment Videos

Generalized atrophic dells in a newborn.

Robert L Buka1, Brandie J Roberts, Brooke Resh

  • 1Division of Pediatric Dermatology, Children's Hospital, San Diego, California, USA. rbuka@md.northwestern.edu

Cutis
|August 15, 2006
PubMed
Summary

Infantile myofibromatosis (IM) is a rare, locally invasive tumor. This report details an unusual case of the atrophic variant of infantile myofibromatosis.

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Area of Science:

  • Pediatric Oncology
  • Dermatopathology
  • Soft Tissue Tumors

Background:

  • Infantile myofibromatosis (IM) is a benign, locally invasive neoplasm presenting in infancy.
  • Its behavior is often hamartomatous, with uncertain cellular origin (fibroblast vs. smooth muscle myocyte).
  • Lesions vary in size and typically do not metastasize.

Purpose of the Study:

  • To report an unusual case of infantile myofibromatosis.
  • To highlight the atrophic variant of this rare condition.

Main Methods:

  • Case presentation of a patient with infantile myofibromatosis.
  • Clinical and pathological review of the atrophic variant.

Main Results:

  • The patient presented with an unusual manifestation of infantile myofibromatosis.

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  • The atrophic variant represents a distinct clinical presentation of IM.

    • Conclusions:

    • Infantile myofibromatosis can present with diverse morphologies, including an atrophic variant.
    • Further research may clarify the specific cell of origin and behavior of different IM variants.