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Updated: Aug 6, 2026
An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells
Published on: September 12, 2019
[Leydig cell tumor: our experience. Bibliographic review]
Ignacio Rubio Tortosa1, Vicente Rodrigo Guanter, Marta García Torrelles
1Servicio de Urología, Hospital Doctor Peset, Valencia, España. nachorutor@hotmail.com
Objectives:
To report the case-series of Leydig cell tumors diagnosed at our center, and to perform a bibliographic review on the topic.
Methods:
Retrospective review of the clinical records of all patients with the diagnosis of Leydig cell tumor in our center over the last 12 years. We evaluated the clinical, diagnostic and therapeutic features, as well as outcomes.
Results:
Four patients were diagnosed and treated in our department over this period. Mean patient age of the time of diagnosis was 51 years. Each of our cases have a different presentation. The two patients who underwent sperm analysis had azoospermia. None of the cases showed anomalous hormonal studies. Seventy-five percent of the cases showed ultrasound signs compatible with testicular neoplasia. In all of them surgical treatment was undertaken (inguinal orchyectomy); one of the patients underwent chemotherapy due to metastasis, having a good response. Mean follow-up is 76 months.
Conclusions:
It is a rare testicular tumor. Inguinal orchyectomy is the treatment of choice. Its good outcome is remarkable.
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