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Related Experiment Videos

Late onset Behçet's disease.

Nelly Ziadé1, Hassane Awada

  • 1Rheumatology Department, Hotel-Dieu de France Hospital, Beirut, Lebanon. nellziade@yahoo.fr

Joint Bone Spine
|August 15, 2006
PubMed
Summary
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Late-onset Behçet

Area of Science:

  • Rheumatology
  • Ophthalmology
  • Dermatology

Background:

  • Behçet's disease typically affects young adults and is defined by recurrent oral ulcers and other symptoms.
  • Late-onset Behçet's disease (after age 60) is exceptionally rare.

Observation:

  • This study presents two cases of Behçet's disease with onset after age 70.
  • Case 1: A 70-year-old male with arthritis, uveitis, oral ulcers, and skin lesions, responsive to corticosteroids.
  • Case 2: A 72-year-old female with uveitis, retinal vasculitis, and skin ulcers, with a family history, stabilized by immunosuppressants.

Findings:

  • The cases highlight that Behçet's disease can manifest in individuals over 70.
  • Both patients exhibited characteristic symptoms, including oral and genital ulcers, ocular inflammation, and skin lesions.

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  • Treatment with corticosteroids and immunosuppressants proved effective in managing symptoms.
  • Implications:

    • Early diagnosis of Behçet's disease is crucial, even in older patients.
    • Prompt and adequate treatment can prevent severe ophthalmic and systemic complications.
    • Recognizing late-onset Behçet's disease expands the understanding of its clinical spectrum.