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Updated: Jul 12, 2026

A Protocol for Analyzing Hepatitis C Virus Replication
Published on: June 26, 2014
Treating viral hepatitis C: efficacy, side effects, and complications
M P Manns1, H Wedemeyer, M Cornberg
1Department of Gastroenterology, Hepatology, and Endocrinology, Medical School of Hannover, Carl-Neuberg-Str 1, D-30625 Hannover, Germany. manns.michael@mh-hannover.de
Abstract:
The treatment of hepatitis C has dramatically improved over the past decade. Unlike any other chronic viral infection, a significant proportion of patients with chronic hepatitis C can be cured. However, the current standard therapy--pegylated interferon alpha and ribavirin--has its limitations. Limited efficacy in patients with hepatitis C virus (HCV) genotype 1 and the side effect profile will necessitate the development of new therapeutic approaches. This review describes the efficacy and optimisation of the current standard therapy of hepatitis C and its problems in special patient populations. New treatment directions beyond interferon alpha based therapies are on the horizon.
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