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Updated: Jul 1, 2026

High-throughput Quantitative Real-time RT-PCR Assay for Determining Expression Profiles of Types I and III Interferon Subtypes
10:00

High-throughput Quantitative Real-time RT-PCR Assay for Determining Expression Profiles of Types I and III Interferon Subtypes

Published on: March 24, 2015

Role of deficient type III interferon-lambda production in asthma exacerbations

Marco Contoli1, Simon D Message, Vasile Laza-Stanca

  • 1Department of Respiratory Medicine, National Heart and Lung Institute, Imperial College London, Norfolk Place, London W2 1PG, UK.

Nature Medicine
|August 15, 2006
PubMed
Summary

Asthma patients show reduced interferon-lambda production in response to rhinovirus, increasing susceptibility to infections and exacerbations. This deficiency correlates with asthma severity and viral load, suggesting new treatment strategies.

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