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A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
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Probing the activation-promoted structural rearrangements in preassembled receptor-G protein complexes

Céline Galés1, Joost J J Van Durm, Stéphane Schaak

  • 1Department of Biochemistry and Groupe de Recherche Universitaire sur le Médicament, Institute for Research in Immunology and Cancer, Université de Montréal, P.O. Box 6128, Downtown station, Montreal, Quebec, Canada H3C 3J7.

Nature Structural & Molecular Biology
|August 15, 2006
PubMed

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