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Updated: Aug 6, 2026

An Orthotopic Sciatic Nerve Xenograft for Neurofibromatosis Type 1 Neurofibromas
Published on: October 10, 2025
Plexiform neurofibroma in type 1 neurofibromatosis
Connie A Keehn1, Pearl Myers, Charles N Paidas
1University of South Florida College of Medicine, Department of Pathology, Tampa, FL 33612, USA. ckeehn@hsc.usf.edu
Abstract:
A 13-year-old African-American girl was admitted to the hospital for surgery. She was diagnosed with Type I neurofibromatosis at the age of 1 year after she was noted to have multiple café au lait spots. Her past medical history included a history of neurofibroma in the base of the brain, treated with radiation therapy and ventriculoperitoneal shunt, as well as a recent diagnosis of bilateral optic gliomas, treated with chemotherapy. Family history was negative for neurofibromatosis.
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