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Prevalence of cardiovascular risk factors in Indian patients undergoing coronary artery bypass surgery
R R Kasliwal1, A Kulshreshtha, Sweta Agrawal
1Escorts Heart Institute and Research Centre, New Delhi.
Insights
Cardiovascular risk factors like diabetes, hypertension, and dyslipidemia are highly prevalent in Indian patients undergoing coronary artery bypass graft surgery (CABG). This highlights the need for better risk management strategies in this population.
Area of Science:
- Cardiology
- Public Health
- Epidemiology
Background:
- Conventional cardiovascular risk factors (CVRFs) significantly impact outcomes after coronary artery bypass graft surgery (CABG).
- The prevalence of CVRFs is rising in the Indian population.
- Data on CVRF prevalence in Indian CABG patients is lacking.
Purpose of the Study:
- To determine the prevalence of major CVRFs in Indian patients undergoing elective CABG.
- To analyze the distribution of these risk factors based on demographics such as age and sex.
Main Methods:
- A cross-sectional study included 1000 consecutive patients undergoing elective CABG.
- Data on major CVRFs including BMI, diabetes, hypertension, dyslipidemia, and smoking history were collected.
- Prevalence rates were calculated for the overall cohort and stratified by sex and age groups.
Main Results:
- High prevalence of CVRFs was observed: 47.5% had diabetes, 70.9% had hypertension, and 85.6% had dyslipidemia.
- Over 95% of patients had at least one major CVRF, with only 4.1% being risk-factor-free.
- Younger patients (<45 years) showed higher rates of dyslipidemia, family history of premature CAD, and smoking compared to older patients.
Conclusions:
- Indian patients undergoing CABG exhibit a high prevalence of conventional cardiovascular risk factors, particularly diabetes, hypertension, and dyslipidemia.
- These findings underscore the importance of addressing CVRFs in this patient group.
- The study highlights demographic variations in risk factor prevalence, with younger patients presenting unique risk profiles.
Background:
Conventional cardiovascular risk factors (CVRFs) are known to influence short-term and long-term outcome following coronary artery bypass graft surgery (CABG). There has been recent increase in prevalence of CVRFs in general population in India. However no information is available regarding the prevalence of same in patients undergoing CABG.
Methods And Results:
In this cross-sectional study, one thousand consecutive patients undergoing elective CABG were included and data on major CVRFs was obtained in them. Mean age of the patients was 59.73 +/- 9.5 years and 884/1000 (88.4%) patients were males. 505/994 (50.8%) patients had BMI > or = 25.0 kg/m2 and 747/994 (75.2%) had BMI > or = 23.0 kg/m2. Diabetes mellitus was present in 475/1000 (47.5%) patients (46.5% men and 55.2% women), hypertension in 709/1000 (70.9% overall; 70.8% men and 71.6% women) and dyslipidemia in 781/913 patients (85.6% overall; 84.5% men and 93.9% women). 213/913 (23.3%) patients had LDL > or = 100mg/dl, 662/913 (72.5%) patients had low HDL and 338/913 (37.0%) patients had elevated triglycerides. 199/1000 (19.9%) patients (18.7% men and 29.3% women) had family history of premature CAD and 545/1000 (54.5%) patients (53.4% men and 62.9% women) had at least one family member having CAD (irrespective of the age of onset). 94/1000 (9.4%) patients (10.4% men and 1.7% women) were current smokers and another 302/1000 (30.2% overall; 33.7% men and 3.4% women) had history of smoking in the preceding one year. 876/913 (95.9%) of all the patients had at least one of the five major CVRFs and only 37/ 913 (4.1%) patients (4.1% men and 4.3% women) were free of all these risk factors. Sixty-one of the 1000 patients (6.1%) were younger than 45.0 years of age. As compared to older patients, dyslipidemia, family history of premature CAD and smoking were commoner in patients less than 45 years of age. In contrast, diabetes and hypertension were more prevalent in the older individuals.
Conclusions:
The present study showed high prevalence of most of the conventional CVRFs, esp. diabetes, hypertension and dyslipidemia in Indian population undergoing CABG.
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