[Rotaviruses and adenoviruses as etiologic factors of diarrhoeas at children]

Iwona Ponurkiewicz1, Piotr Sienkiewic, Paulina Masalska

  • 1Laboratorium SP ZOZ w Hajnówce.

Insights

Rotavirus and adenovirus are common causes of viral diarrhea in young children. This study found rotavirus in 35.8% of hospitalized children with acute diarrhea, highlighting its prevalence.

Area of Science:

  • Pediatrics
  • Virology
  • Epidemiology

Context:

  • Viral diarrheas pose a significant clinical and epidemiological challenge, particularly in pediatric populations.
  • Acute diarrhea is a common reason for hospitalization in children.
  • Hospital-acquired infections are a concern in pediatric wards.

Purpose:

  • To investigate the prevalence of rotavirus and adenovirus infections in children hospitalized with acute diarrhea.
  • To assess the incidence of hospital infections in a pediatric ward.
  • To describe the epidemiological characteristics of viral diarrhea in a temperate climate.

Summary:

  • A study of 218 children (0-7 years) hospitalized with acute diarrhea between 2004-2005 in Hajnowka revealed rotavirus infection in 35.8% and adenovirus in 5.1%.
  • Hospital-acquired infections were noted in 0.96% of children admitted for other reasons.
  • The observed morbidity exhibited seasonal patterns typical of temperate climates.

Impact:

  • Provides crucial data on the etiological agents of viral diarrhea in pediatric populations.
  • Informs public health strategies for the prevention and control of childhood diarrheal diseases.
  • Contributes to understanding the epidemiology of viral gastroenteritis in a specific geographic region.

Related Concept Videos

Respiratory Syncytial Virus Disease01:29

Respiratory Syncytial Virus Disease

Human respiratory syncytial virus (RSV) is a widespread pathogen that primarily targets infants and young children but also poses a serious health risk to elderly and immunocompromised individuals. Belonging to the Pneumoviridae family, RSV is a negative-sense, single-stranded RNA virus within the Pneumovirus genus. Its global health burden is significant, with millions of cases annually resulting in hospitalizations and mortality, particularly in resource-limited settings. Although most...
Bacterial Gastroenteritis01:18

Bacterial Gastroenteritis

Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...
Poliomyelitis01:17

Poliomyelitis

Poliomyelitis is caused by poliovirus, a small, non-enveloped, positive-sense RNA virus of the Picornaviridae family and Enterovirus genus. Transmission occurs primarily via the fecal-oral route, often through ingestion of contaminated water or food. The virus initially replicates in the oropharynx and intestinal mucosa, particularly in lymphoid tissues such as the tonsils, Peyer’s patches, and regional lymph nodes. Primary viremia follows, allowing dissemination throughout the body.In most...
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
Mechanisms of Retrovirus-induced Cancers01:51

Mechanisms of Retrovirus-induced Cancers

Retroviruses are RNA viruses that have been shown to cause cancers in diverse species, including chickens, mice, cats, and monkeys. The RNA genomes of these viruses are first reverse-transcribed into single and then double-stranded DNA (dsDNA) copies. This dsDNA called proviral DNA then integrates into the host genome. Subsequently, the host cell transcribes the proviral DNA in concert with the chromosomal DNA. This leads to the production of viral RNA and proteins that assemble at the host...