[C-reactive protein in cardiovascular risk evaluation]

Damir Fabijanić1, Marko Banić, Dusko Kardum

  • 1Klinika za unutarnje bolesti Klinicke bolnice Split, lokalitet Kriline, Split. damir.fabijanic@st.t-com.hr

Lijecnicki Vjesnik
|August 17, 2006
PubMed

Insights

High-sensitive C-reactive protein (hs-CRP) indicates elevated cardiovascular risk and helps monitor treatment effectiveness. Elevated hs-CRP levels signal increased risk for cardiovascular events and guide preventive therapies.

Area of Science:

  • Cardiovascular Medicine
  • Inflammation Biology
  • Biomarker Research

Context:

  • Atherosclerosis involves inflammation, impacting cardiovascular risk.
  • Global cardiovascular risk assessment necessitates reliable inflammatory markers.
  • High-sensitive C-reactive protein (hs-CRP) is a key inflammatory marker.

Purpose:

  • To review the role of hs-CRP in atherosclerosis pathogenesis.
  • To discuss the clinical applications of hs-CRP in cardiovascular disease.
  • To evaluate hs-CRP for risk stratification and therapeutic monitoring.

Summary:

  • hs-CRP levels above 3 mg/L identify increased risk for cardiovascular events in diverse patient groups.
  • Pharmacological and lifestyle interventions that reduce cardiovascular events also lower hs-CRP.
  • hs-CRP aids in identifying high-risk individuals, monitoring disease activity, and assessing treatment efficacy.

Impact:

  • hs-CRP serves as a valuable tool for primary and secondary cardiovascular prevention strategies.
  • Understanding hs-CRP's role enhances clinical practice in managing atherosclerosis.
  • hs-CRP levels can guide targeted therapeutic interventions for cardiovascular health.

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