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09:02
Infection of Primary Nasal Epithelial Cells Grown at an Air-Liquid Interface to Characterize Human Coronavirus-Host Interactions
Published on: September 22, 2023
Human coronavirus NL63, a new respiratory virus
Lia van der Hoek1, Krzysztof Pyrc, Ben Berkhout
1Department of Human Retrovirology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. c.m.vanderhoek@amc.uva.nl
FEMS Microbiology Reviews
|August 17, 2006
Summary
Human coronaviruses include HCoV-229E, HCoV-OC43, SARS-CoV, and HCoV-NL63. This overview details research findings on the human coronavirus NL63 (HCoV-NL63).
Area of Science:
- Virology
- Infectious Diseases
- Public Health
Background:
- Historically, only two human coronaviruses (HCoV-229E, HCoV-OC43) were known.
- The emergence of SARS-CoV in 2003 highlighted the potential for novel human coronaviruses.
- HCoV-NL63 was identified in 2004, expanding the known spectrum of human coronavirus infections.
Purpose of the Study:
- To provide a comprehensive overview of the existing scientific literature on HCoV-NL63.
- To synthesize key findings from research on this emerging human coronavirus.
Main Methods:
- Literature review of publications related to HCoV-NL63.
- Systematic analysis of research findings on HCoV-NL63 characteristics and impact.
Main Results:
- HCoV-NL63 represents a significant addition to the known human coronavirus family.
- Research has elucidated various aspects of HCoV-NL63 since its discovery.
- The overview consolidates current knowledge on HCoV-NL63.
Conclusions:
- HCoV-NL63 is an important human pathogen requiring continued research.
- Understanding HCoV-NL63 is crucial for managing respiratory infections.
- This review serves as a valuable resource for researchers studying HCoV-NL63.
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