Related Experiment Video
Updated: Aug 6, 2026

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
Published on: August 13, 2019
Alternatives to hormone replacement therapy: a multi-method study of women's experiences
1Department of Psychiatry and Behavioural Neurosciences, McMaster University, Patterson Building, Chedoke Hospital, West Hamilton, Ont., Canada L8N 3Z5. wathenn@mcmaster.ca
Objective:
To explore women's decision-making regarding use of complementary and alternative medicines (CAM) during menopause.
Methods:
Qualitative interviews were conducted with 20 women who were currently or had previously used hormone replacement therapy (HRT), including questions about their experiences with alternatives to HRT. This was followed by a non-random questionnaire survey of 285 demographically representative Canadian women aged 45-65 who were current or former HRT users.
Results:
Fifty-seven percent (57%, n = 162) of women reported either having used or considered a CAM approach for menopause. Women who had tried or considered CAM were significantly younger (mean age = 54.9 years versus 56.8 years; t(280) = 3.4, p < .05) and reported experiencing worse menopause-specific symptoms than those who had not, and these women also reported a worse experience of menopause overall.
Conclusion:
: A majority of menopausal women in the current study considered or tried CAM alternatives to HRT.
Related Concept Videos
Birth Control Methods
Menopause
Hormonal Regulation
Pharmaceutical Alternatives: Stability-Related Therapeutic Nonequivalence
