[A long-term survival case after resection for umbilical metastasis from gastric cancer treated with weekly...

We report a patient with umbilical metastasis of gastric cancer (Sister Mary Joseph' s nodule) who has been treated by weekly paclitaxel for 16 months after resection of an umbilical tumor. A 61-year-old man who underwent total gastrectomy for cytology-positive advanced gastric cancer in March 2002 and received TS-1 after surgery for 2 years, complained of abdominal pain in May 2004. Physical examination and computed tomography showed an umbilical nodule about 20 mm in diameter. An excisional biopsy of umbilical tumor was performed, and the umbilical metastasis and peritoneal dissemination were diagnosed histopathologically. Weekly paclitaxel was administered after resection of umbilical metastasis. The patient has been alive with good performance status and normal level of serum tumor markers after 48 administrations of paclitaxel.