Related Experiment Video
Updated: Aug 6, 2026
08:30
Investigating von Willebrand Factor Pathophysiology Using a Flow Chamber Model of von Willebrand Factor-platelet String Formation
Published on: August 14, 2017
[Acquired von Willebrand syndrome]
1Servizio di Immunoematologia e Trasfusione, Centro Emofilia, Azienda Ospedaliera, Verona. mfranchini@univr.it
Recenti Progressi in Medicina
|August 18, 2006
Summary
Acquired von Willebrand syndrome (aVWS) is a rare bleeding disorder that mimics congenital von Willebrand disease. It develops in patients without a prior bleeding history, often linked to other serious conditions.
Area of Science:
- Hematology
- Internal Medicine
- Rare Diseases
Context:
- Acquired von Willebrand syndrome (aVWS) is a rare bleeding disorder.
- It presents similarly to congenital von Willebrand disease (VWD).
- aVWS occurs in individuals without a personal or family history of bleeding disorders.
Purpose:
- To review the key aspects of acquired von Willebrand syndrome.
- To provide concise information on its pathophysiology, clinical features, diagnostics, and treatment.
- To highlight its association with other underlying medical conditions.
Summary:
- aVWS mimics congenital VWD in clinical and laboratory findings but arises acquired.
- It is associated with lymphoproliferative disorders, myeloproliferative disorders, and cardiovascular diseases.
- This review covers the main pathogenic, clinical, laboratory, and therapeutic aspects.
Impact:
- Improves understanding of aVWS, a potentially underdiagnosed bleeding disorder.
- Aids clinicians in diagnosing and managing patients with aVWS.
- Facilitates recognition of the link between aVWS and other systemic diseases.
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