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Past and current trends in soy supplementation: a bibliographic study
M Farriol1, M Jordà, G Delgado
1Centro de Investigación Bioquímica y Biología Molecular, Hospital Vall d'Hebron, Barcelona, Spain. mfarriol@ir.vhebron.net
Soy isoflavone supplementation shows promise in clinical trials, particularly for healthy individuals. Emerging research suggests potential benefits for elite athletes, indicating a new therapeutic application.
Area of Science:
- Nutritional Science
- Clinical Research
- Bibliometrics
Background:
- Soy isoflavones have diverse therapeutic applications explored in clinical trials.
- Bibliographic analysis is crucial for understanding research trends and identifying new uses.
Purpose of the Study:
- To identify predominant therapeutic areas of soy isoflavone use in clinical trials.
- To assess emerging fields of soy isoflavone application through bibliographic resource analysis.
Main Methods:
- Searched MEDLINE database up to December 31, 2004, for clinical trials on soy.
- Reviewed 86 selected abstracts, assessing variables and subject demographics (n=3280).
- Analyzed study focus, including metabolite levels, hormone/lipid profiles, and specific populations.
Main Results:
- Most studies (71%) involved healthy individuals, with a focus on metabolite, hormone, and lipid profiles.
- Postmenopausal women constituted a significant portion of participants (71%).
- After 2000, two studies highlighted positive results in elite athletes (gymnasts, judoists).
Conclusions:
- Soy isoflavone research has historically focused on healthy populations and metabolic profiles.
- The competitive sports elite represents an emerging area for soy supplementation research.
- Soy supplementation may offer potential benefits for athletic performance and recovery.
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