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Neuroanatomy and physiology of ejaculation.

François Giuliano¹, Pierre Clement

¹Pelvipharm Laboratories, Neuro-Urology Unit, Department of Physical Medicine and Rehabilitation, Raymond Poincaré Hospital, Garches, France. giuliano@cyber-sante.org

Annual Review of Sex Research

|August 18, 2006

Summary

Normal male ejaculation involves two phases: emission and expulsion. This process requires intricate coordination between the nervous system

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Area of Science:

Reproductive biology
Neuroscience
Physiology

Background:

Ejaculation is the expulsion of sperm from the male urethra.
It comprises two distinct phases: emission and expulsion.
Normal ejaculation necessitates coordinated neural control.

Purpose of the Study:

To elucidate the neuroanatomical and physiological underpinnings of normal male ejaculation.
To detail the coordinated roles of the autonomic and somatic nervous systems in ejaculation.

Main Methods:

Review of neuroanatomical pathways involved in ejaculation.
Analysis of physiological control mechanisms governing emission and expulsion phases.
Examination of spinal and supraspinal regulatory centers.

Main Results:

Ejaculation involves coordinated sympathetic, parasympathetic, and somatic nervous system activity.
Peripheral anatomical structures (glands, ducts, muscles) are controlled by spinal centers.
Spinal ejaculatory centers receive input from genital sensory afferents and supraspinal brain regions.

Conclusions:

Normal antegrade ejaculation is a complex reflex requiring precise neural integration.
Spinal cord nuclei act as central ejaculatory generators, modulated by sensory and descending brain signals.
Understanding these pathways is crucial for addressing ejaculatory dysfunctions.

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