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Study of expression of genes affecting hematopoiesis maintenance in stromal cell lines obtained from TNF-deficient

F N Rozov1, I N Nifontova, A V Belyavskii

  • 1Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, ul. Vavilova 32, Moscow 117984, Russia.

Doklady. Biochemistry and Biophysics
|August 18, 2006
PubMed
Abstract

No abstract available in PubMed .

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Regulation of Hematopoietic Stem Cells01:01

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All blood and immune cells are produced from the multipotent hematopoietic stem cells (HSCs) by the process of hematopoiesis. However, they all have a limited life span. In addition, many are depleted in immune surveillance or combatting an injury or infection. This makes blood one of the most regenerative tissues. Hematopoiesis helps replenish these blood and immune cells, restoring the body's normal functioning. However, overproduction of blood and immune cells can make them cancerous or...
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Commitment is the  process whereby stem cells:

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