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Published on: May 6, 2018
Systemic allergic reactions to aprotinin injection around the Achilles tendon
Nicholas J Rukin1, Nicola Maffulli
1Department of Trauma and Orthopaedic Surgery, Keele University School of Medicine, Thornburrow Drive, Hartshill, Stoke-on-Trent, Staffordshire, England.
Abstract:
Local aprotinin injections are used in the treatment of chronic tendinopathy. Severe allergic reactions, although uncommon, have been reported. We highlight two instances of systemic allergic reaction, and discuss the potential side effects of local aprotinin injections in the orthopaedic setting as well as the evidence base for its use.
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