The mid-term outcome of the Cox maze III procedure and complex concomitant cardiac surgery

Ulf Lockowandt1

  • 1Department of Cardiothoracic Surgery and Anesthesiology, Karolinska University Hospital, Stockholm, Sweden. ulf.lockowand@karolinska.se

Insights

The Cox maze III procedure is a safe and effective addition to complex cardiac surgery for controlling atrial fibrillation. This study shows high success rates in patients with persistent or permanent atrial fibrillation.

Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Electrophysiology

Background:

  • Atrial fibrillation is a common arrhythmia often managed separately from other cardiac surgeries.
  • Many surgeons avoid maze procedures during complex cardiac operations.
  • The Cox maze III procedure offers a potential solution for concurrent atrial fibrillation treatment.

Purpose of the Study:

  • To evaluate the safety and efficacy of the Cox maze III procedure when performed concurrently with other complex cardiac surgeries.
  • To assess the impact of this combined approach on atrial fibrillation control.

Main Methods:

  • A cohort of 40 patients (mean age 56 years) with persistent or permanent atrial fibrillation underwent the Cox maze III procedure alongside other cardiac surgeries.
  • Patient data, including pre-operative atrial fibrillation duration and follow-up duration (22-82 months), were analyzed.
  • Outcomes assessed included mortality, re-operations, pacemaker dependency, and freedom from atrial fibrillation.

Main Results:

  • The 30-day mortality was 2.5%, with low rates of re-operation (5%) for bleeding or other complications.
  • Late mortality was also 2.5%, and 14% of patients required postoperative pacemakers.
  • Crucially, 97% of patients achieved freedom from atrial fibrillation post-procedure.

Conclusions:

  • The Cox maze III procedure can be safely and effectively integrated into complex cardiac surgery.
  • This combined approach demonstrates excellent long-term control of atrial fibrillation.
  • The findings support the routine consideration of the Cox maze III procedure in appropriate cardiac surgery patients.
Abstract

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