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Diffuse lung cysts in lymphoid interstitial pneumonia: high-resolution CT and pathologic findings
C Isabela S Silva1, Julia D Flint, Robert D Levy
1Department of Radiology, Vancouver General Hospital, University of British Columbia 899 West 12th Avenue, Vancouver, BC, Canada. isabela.silva@vch.ca
Journal of Thoracic Imaging
|August 18, 2006
Summary
Lymphoid interstitial pneumonia (LIP) can present with extensive pulmonary cysts, a rare finding. This case highlights extensive cystic disease in LIP, a unique presentation preceding lung transplantation.
Area of Science:
- Pulmonology
- Radiology
- Pathology
Background:
- Lymphoid interstitial pneumonia (LIP) is a pulmonary lymphoproliferative disorder often associated with autoimmune diseases or immunodeficiency.
- Typical high-resolution computed tomography (HRCT) findings include ground-glass opacities, nodules, and scattered cysts.
Observation:
- This case report details a 64-year-old male with idiopathic LIP.
- The patient presented with extensive pulmonary cysts as the predominant HRCT finding, an unusual manifestation of LIP.
Findings:
- Extensive cystic lung disease was the primary HRCT finding in this case of idiopathic LIP.
- The patient subsequently underwent a unilateral lung transplant.
Implications:
- This case expands the understanding of LIP's spectrum of radiologic manifestations.
- The presentation of extensive cystic disease in LIP, particularly in the context of lung transplantation, is novel and warrants further investigation.
