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Updated: Jul 26, 2026
04:48
Chemotherapy-induced Vascular Toxicity - Real-time In vivo Imaging of Vessel Impairment
Published on: January 7, 2015
[Chemotherapy induced-vomiting--a practical guide for prevention and therapy]
K Jordan1, W Voigt, H-J Schmoll
1Klinik für Innere Medizin IV, Hämatologie/Onkologie, Martin-Luther-Universität Halle/Wittenberg, Ernst-Grube-Strasse 40, 06120 Halle/Salle. Karin.jordan@medizin.uni-halle.de
Deutsche Medizinische Wochenschrift (1946)
|August 18, 2006
Summary
Chemotherapy-induced nausea and vomiting are distressing. New antiemetic therapies combining neurokinin-1-receptor-antagonists, 5-HT(3) receptor-antagonists, and steroids protect 70-90% of patients from emesis.
Area of Science:
- Oncology
- Pharmacology
- Gastroenterology
Context:
- Nausea and vomiting are significant adverse effects of chemotherapy.
- The severity of these side effects is linked to the emetogenic potential of chemotherapy drugs.
Purpose:
- To describe recent advancements in antiemetic therapy.
- To outline current guidelines for antiemetic prophylaxis.
Summary:
- Modern antiemetic regimens, particularly those combining neurokinin-1-receptor-antagonists, 5-HT(3) receptor-antagonists, and steroids, are highly effective.
- These combination therapies can protect 70-90% of patients undergoing highly emetogenic chemotherapy from nausea and vomiting.
Impact:
- Improved patient quality of life during chemotherapy.
- Enhanced adherence to necessary cancer treatments.
- Reduced healthcare burden associated with managing chemotherapy side effects.
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