Related Experiment Video
Updated: Aug 6, 2026

09:36
Dual-Dye Optical Mapping of Hearts from RyR2R2474S Knock-In Mice of Catecholaminergic Polymorphic Ventricular Tachycardia
Published on: December 22, 2023
A low-cost high-efficiency fiber-optic coupler for recording action potentials within the myocardial wall
Salim F Idriss1, Ann M Pitruzzello
1Division of Pediatric Cardiology, Department of Pediatrics, Duke University Medical Center, Durham, NC 27710, USA. salim.idriss@duke.edu
IEEE Transactions on Bio-Medical Engineering
|August 19, 2006
Abstract:
We present a high-efficiency, low-cost wavelength division multiplexer to record cardiac optical action potentials (APs) within the myocardial wall using optical fibers. APs with signal-to-noise ratio as high as 60, without spatial or temporal averaging, and as high as 200, with median-filtering, were recorded in rabbit ventricle.

