Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Systematic reviews and knowledge translation.

Peter Tugwell1, Vivian Robinson, Jeremy Grimshaw

  • 1Centre for Global Health, Institute of Population Health, University of Ottawa, Ottawa, Ontario, Canada.

Bulletin of the World Health Organization
|August 19, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reply of the authors: "World Health Organization infertility guidelines, 2025".

Fertility and sterility·2026
Same author

MAKING CLINICAL PRACTICE GUIDELINES FOR DENTISTRY MORE PATIENT-CENTERED THROUGH PATIENT-REPORTED OUTCOME INTEGRATION.

The journal of evidence-based dental practice·2026
Same author

Reply: Concerns regarding the WHO guideline on infertility: implications for contemporary reproductive medicine.

Human reproduction (Oxford, England)·2026
Same author

Theory and behaviour change techniques informing strategies to improve recruitment to clinical trials: a systematic review of randomised evaluations.

Trials·2026
Same author

Response to letters about Hypertension Canada guideline.

Canadian family physician Medecin de famille canadien·2026
Same author

New GRADE Evidence-to-Decision Framework for Pairwise and Multiple Comparisons (GRADE Guidance 45).

Annals of internal medicine·2026

Effective health interventions reach poorer populations less often. A new framework guides equitable knowledge translation to improve access and effectiveness for disadvantaged groups, ensuring health equity.

Area of Science:

  • Global Health
  • Health Equity
  • Knowledge Translation

Background:

  • Effective interventions exist to meet global health goals, but their uptake is significantly lower in the poorest populations.
  • A "staircase" effect of reduced coverage, diagnostic accuracy, provider compliance, and consumer adherence diminishes intervention effectiveness in disadvantaged groups.

Purpose of the Study:

  • To propose an evidence-based framework for equity-oriented knowledge translation.
  • To enhance the community effectiveness of interventions and promote health equity.

Main Methods:

  • Developed a cascade framework to systematically assess and prioritize barriers to intervention uptake.
  • Tailored knowledge translation strategies for diverse audiences including the public, patients, practitioners, policymakers, press, and the private sector.

Related Experiment Videos

  • Included evaluation, monitoring, and sharing of implementation strategies.
  • Main Results:

    • The framework provides a systematic method for decision-makers to apply evidence-based knowledge in disadvantaged populations.
    • Illustrated framework application using insecticide-treated bednets for malaria prevention and childhood immunization.
    • Highlighted the need for empirical validation and evaluation of the framework's usefulness.

    Conclusions:

    • The proposed framework offers a guide for researchers and implementers to plan equitable knowledge translation strategies.
    • Encourages policymakers and health managers to utilize the framework for implementing effective interventions in diverse settings.
    • Emphasizes the importance of addressing disparities to achieve universal health goals.