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Towards a definition of intractable headache for use in clinical practice and trials

P J Goadsby1, J Schoenen, M D Ferrari

  • 1Headache Group, Institute of Neurology, London, UK. peterg@ion.ucl.ac.uk

Cephalalgia : an International Journal of Headache
|August 22, 2006
PubMed
Abstract

No abstract available in PubMed .

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Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...

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