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Published on: May 14, 2021
An unusual case of secondary fibrosarcoma after treatment for breast cancer
Francesco Plotti1, Violante Di Donato, Marzio Angelo Zullo
1Department of Gynecology, Obstetrics and Perinatology, University of Rome La Sapienza, Viale del Policlinico 155-00161 Rome, Italy. francescoplotti@tiscali.it
Background:
Post-irradiation breast sarcoma is a rare and highly aggressive tumor, associated with poor prognosis. However, the mean latent periods reported for postradiation sarcomas after treatment of breast cancer ranges from 5 to 10 years.
Case:
We present a rare case of fibrosarcoma of the axilla, diagnosed 23 months after breast surgery and irradiation for medullary poorly differentiated carcinoma, treated with wide local excision with resection of the serratus anterior muscle until pleural wall.
Conclusion:
This case confirm a possible early appearance of sarcoma in the irradiation field after radiotherapy. Thus, when a nodule appears in the irradiation field even if within 2 years after radiotherapy, physician should be alert for a possible sarcoma and wide biopsy with histologic confirmation is auspicable.
