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[Effect of long-term intake of Y3+ in drinking water on learning-memeory functions and growth-development of rats]
Min-Yi Wu1, Ping Zhang, Wei-Dong Yang
1Department of Biotechnology, Jinan University, Guangzhou 510632, China.
Objective:
The aim of this paper was to learn the effect of long-term intake of Y3+ in drinking water on learning-memory function and growth-development of rats.
Methods:
The rats were fed with water dissolved different level Y3+ (0, 0.534, 53.4, 5340 mg/L) for 6 months, pregnant rate, survive rate, bear rate, variety in weight were calculated, the learning-memory function was observed by step-down test.
Results:
The results showed that a significantly decrease in electric shock period and an increase in incubation period were observed for the low dose group, in contrast, a significantly increase in electric shock period and error times, and an decreases in weight and survive rate were observed for the high dose group.
Conclusion:
Y3+ in 0.534 mg/L might improve the function of learning and memory in rats, and that Y3+ in 5340mg/L could restrain both the function of learning-memory functions and growth-development in rats.
