Related Experiment Video
Updated: Aug 6, 2026

06:53
Cell Population Analyses During Skin Carcinogenesis
Published on: August 21, 2013
The management of basal cell carcinomas
Irish Medical Journal
|August 23, 2006
Summary
This audit of basal cell carcinoma (BCC) management found significant delays in patient treatment. Frequent biopsies and high referral rates to plastic surgery contributed to these service deficiencies.
Area of Science:
- Dermatology
- Health Services Research
Background:
- Basal cell carcinoma (BCC) has low mortality but high incidence, posing a significant health service burden.
- Audits are crucial for evaluating and improving the management of common dermatological conditions like BCC.
Purpose of the Study:
- To audit the management of basal cell carcinoma (BCC) within a dermatology department.
- To identify service deficiencies and delays in the patient pathway for BCC treatment.
Main Methods:
- Retrospective audit of BCC cases managed by the dermatology department.
- Analysis of patient pathways, including time to treatment and referral patterns.
Main Results:
- Mean delays from first visit to treatment were 62 days (dermatology) and 129 days (plastic surgery).
- Diagnostic incisional biopsies were frequently used (72%) despite accurate clinical diagnosis (90%), causing extra visits.
- Over 50% of BCC cases were referred to plastic surgery, with only 43% treated definitively by dermatology.
Conclusions:
- Current BCC management pathways involve significant delays, often due to unnecessary biopsies and high referral rates.
- Service improvements are planned to streamline BCC treatment and reduce patient waiting times.
More Related Videos
Related Concept Videos
Skin Cancer
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Clinical Applications of Epidermal Stem Cells
Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...
Renewal of Skin Epidermal Stem Cells
The skin is divided into epidermis, dermis, and hypodermis, the skin's outermost, middle, and inner layers. The human epidermal layer regularly undergoes renewal, where old, dead cells are replaced by new cells. Epidermal stem cells or EpiSCs divide and differentiate to restore the lost cells. For the renewal process, some EpiSCs continuously self-renew. In contrast, few others differentiate into transit-amplifying cells, which later form prickle or spinous cells, followed by granular cells,...
