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Updated: Aug 6, 2026

Monitoring Functionality and Morphology of Vasculature Recruited by Factors Secreted by Fast-growing Tumor-generating Cells
Published on: November 23, 2014
[Significance of angiogenesis in malignant tumors]
1Univerzita Karlova v Praze, Lékafski fakulta a Fakultni nemocnice v Hradci Králové: II. interni klinika, Oddĕleni klinické hematologie. smolej@seznam.cz
Abstract:
Angiogenesis, i.e. development of new vessels from preexisting ones, plays a key role in the development and progression of malignant tumors. Increased angiogenesis is the hallmark of virtully all types of cancer and has been identified as an independent adverse prognostic factor in various solid tumors and hematological malignancies. This review summarizes current knowledge about angiogenic process, describes methods of angiogenesis assessment and appreciates antiangiogenic therapy which offers new and perspective options in the treatment of malignancies.
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