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Updated: May 10, 2026

Proliferation and Differentiation of Murine Myeloid Precursor 32D/G-CSF-R Cells
Published on: February 21, 2018
When it comes to decisions, myeloid progenitors crave positive feedback
Dale Muzzey1, Alexander van Oudenaarden
1Department of Physics, Massachusetts Institute of Technology, Cambridge, 02139, USA.
Abstract:
Positive feedback is a ubiquitous feature of networks that establish and maintain cellular decisions. In this issue of Cell, Laslo et al. (2006) demonstrate how a feedback loop comprised of two mutual repressors regulates the differentiation of myeloid progenitors into either macrophages or neutrophils.
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