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Updated: Aug 5, 2026

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder
Published on: April 26, 2024
Bodily symptoms in moderate and severe depression
Lene Nyboe Jacobsen1, Irene Smith Lassen, Preben Friis
1Department of Physical Therapy, Aarhus University Psychiatric Hospital, DK-8240, Risskov, Denmark. lnj@psykiatri.aaa.dk
Patients with severe depression experience more bodily symptoms like muscular tension and pain. These physical symptoms improved significantly as depression severity decreased, suggesting a need for physiotherapy.
Area of Science:
- Psychiatry
- Psychosomatic Medicine
- Clinical Psychology
Background:
- Depression is often associated with physical symptoms, but these are not always fully characterized.
- Understanding the specific bodily complaints in severe depression is crucial for effective treatment.
Purpose of the Study:
- To describe bodily symptoms in patients with moderate to severe depression.
- To compare these symptoms with those of healthy individuals.
- To examine the correlation between depression severity and bodily symptoms.
Main Methods:
- Inpatients (n=29) diagnosed with moderate to severe depression (ICD-10) and 29 matched healthy controls were assessed.
- Bodily symptoms were measured using the Body Awareness Scale (BAS).
- Depression severity was evaluated using the Hamilton Depression Scale (HDS) at admission and discharge.
Main Results:
- Patients with severe depression reported significantly more muscular tension, pain, restricted breathing, negative body attitudes, and reduced movement centering compared to controls (p<0.001).
- A statistically significant improvement in bodily symptoms (p<0.01) was observed alongside a reduction in depression scores.
- Changes in depression severity correlated with changes in bodily symptoms.
Conclusions:
- Severe depression is linked to distinct bodily symptoms and complaints.
- Physiotherapeutic interventions may be beneficial for patients with moderate to severe depression.
- Further investigation into the psychosomatic aspects of depression is warranted.
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