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Predictors of recurrent stroke in African Americans
S Ruland1, D Richardson, E Hung
1Department of Neurology and Rehabilitation, University of Illinois at Chicago, Chicago, IL 60612, USA. sruland@uic.edu
Neurology
|August 23, 2006
Summary
Recurrent stroke is common in African Americans, leading to disability. Hypertension is the most significant modifiable risk factor for stroke recurrence in this population.
Area of Science:
- Neurology
- Epidemiology
- Public Health
Background:
- Stroke incidence and mortality are significantly higher in African Americans compared to white populations.
- Understanding stroke recurrence is crucial for this high-risk demographic.
Purpose of the Study:
- To characterize recurrent stroke patterns in African Americans.
- To identify the predictive value of vascular risk factors for stroke recurrence in this group.
Main Methods:
- The African-American Antiplatelet Stroke Prevention Study followed 1,809 African Americans with recent noncardioembolic ischemic stroke.
- Data collected included recurrent stroke events, subtypes, and resulting disability.
Main Results:
- 10.6% of participants experienced recurrent stroke, often leading to increased disability.
- Elevated systolic blood pressure, pulse pressure, and mean arterial pressure were associated with increased stroke recurrence risk.
- Baseline Glasgow Outcome Score and longitudinal pulse pressure predicted recurrent stroke.
Conclusions:
- Recurrent stroke significantly increases disability, and disability itself is a predictor of further stroke.
- Hypertension emerges as the most critical modifiable risk factor for recurrent stroke in African Americans.
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