Related Experiment Video
Updated: Jul 20, 2026
Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging
Published on: December 15, 2014
[Application of real-time tissue elastography in diagnosis of breast cancer]
Xiu-fang Zhang1, Xue-ming Liu, Xiao-feng Bao
1Department of Ultrasonography, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, China.
Objective:
To investigate the clinical value of real-time tissue elastography (RTE) in the diagnosis of breast cancer.
Methods:
One hundred and twenty patients with breast lumps (135 lesions) were examined with B-mode imaging, color Doppler flowing imaging (CDFI) and RTE. The elastogram was graded using 5-score evaluating method. The postoperative pathological diagnosis was used as gold standard, and the sensitivity, specificity and accuracy of RTE and two-dimensional ultrasonography combined with RTE in diagnosis of breast cancer were calculated.
Result:
When the score >4 was set for cut-off criteria of malignancy, the sensitivity, specificity and accuracy of RTE was 85.45%, 83.75% and 84.4%, respectively. While two-dimensional ultrasonography combined with RTE was used, the sensitivity, specificity and accuracy increased up to 100%, 95% and 97%, respectively.
Conclusion:
RTE combined with two-dimensional ultrasonography can improve the validity in the diagnosis of malignant breast lesions.
