Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Chronic renal function disorders during lithium use].

H A J M van Gerven1, W H Boer

  • 1Centrum voor Ambulante Ouderenpsychiatrie Altrecht, Utrecht.

Nederlands Tijdschrift Voor Geneeskunde
|August 24, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The truth on current peritoneal dialysis: state of the art.

The Netherlands journal of medicine·2017
Same author

Acute reactions to polysulfone/polyethersulfone dialysers: literature review and management.

The Netherlands journal of medicine·2017
Same author

Management of encapsulating peritoneal sclerosis: a guideline on optimal and uniform treatment.

The Netherlands journal of medicine·2011
Same author

Patients' representations of their end-stage renal disease: relation with mortality.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association·2009
Same author

[Fatigue, loss of appetite and anuria due to retroperitoneal fibrosis].

Nederlands tijdschrift voor geneeskunde·2007
Same author

[Polyuria and polydipsia due to renal diabetes insipidus during the use of lithium].

Nederlands tijdschrift voor geneeskunde·2006
Same journal

[Improving mobility in painful osteoarthritis].

Nederlands tijdschrift voor geneeskunde·2026
Same journal

[The effectiveness and costs of the Back At work After Surgery (BAAS) work-integrated care pathway on return to work for patients receiving knee arthroplasty].

Nederlands tijdschrift voor geneeskunde·2026
Same journal

[The rise of genetic therapies: urgent moral and societal questions].

Nederlands tijdschrift voor geneeskunde·2026
Same journal

[A man with a wound on his elbow].

Nederlands tijdschrift voor geneeskunde·2026
Same journal

[Employment of safety net enclosures].

Nederlands tijdschrift voor geneeskunde·2026
Same journal

[The power of a neurodiversity perspective; demedicalizing mental health support].

Nederlands tijdschrift voor geneeskunde·2026
See all related articles

Long-term lithium use can cause kidney problems, including progressive renal failure in some patients. Monitoring kidney function and considering lithium discontinuation are crucial for managing these risks.

Area of Science:

  • Nephrology
  • Psychiatry

Context:

  • Lithium is a cornerstone treatment for bipolar and unipolar depression.
  • Nephrogenic diabetes insipidus is a known adverse effect of lithium therapy.
  • The potential for lithium-induced progressive renal failure remains a subject of ongoing debate.

Purpose:

  • To review the current understanding of lithium's impact on renal function.
  • To discuss management strategies for lithium-associated kidney disease.
  • To highlight the importance of monitoring renal function in patients on long-term lithium treatment.

Summary:

  • Approximately 20% of patients on long-term lithium treatment experience some decline in renal function.
  • Progressive renal failure requiring dialysis is reported in a minority of patients.

Related Experiment Videos

  • Discontinuation of lithium may be considered at serum creatinine levels of 200 micromol/l or creatinine clearance of 40 ml/min.

    • Impact:

    • Identifying patients at risk for progressive renal failure is critical.
    • Management of non-progressive renal failure should focus on cardiovascular risk factors like hypertension and dyslipidemia.
    • Further research is needed to optimize lithium therapy and minimize renal complications.