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Updated: Jul 20, 2026
07:37
Roux-en-Y Gastric Bypass Operation in Rats
Published on: June 11, 2012
Ulcer disease after gastric bypass surgery
Ramsey M Dallal1, Linda A Bailey
1Albert Einstein Healthcare Network, Philadelphia, PA USA. dallalr@einstein.edu
Summary
Marginal ulcers after laparoscopic gastric bypass occurred in 3.5% of patients, presenting as bleeding, pain, or perforation. Medical management with proton pump inhibitors and sucralfate was effective, with no identified preoperative risk factors.
Area of Science:
- Bariatric Surgery
- Gastroenterology
- Surgical Complications
Background:
- Marginal ulceration following laparoscopic gastric bypass (LGB) is a known complication.
- The precise mechanisms and predictive factors remain incompletely understood.
- This study investigates the incidence, presentation, and outcomes of marginal ulcers in LGB patients.
Purpose of the Study:
- To determine the incidence of marginal ulcer disease after laparoscopic gastric bypass.
- To describe the clinical presentation and outcomes of marginal ulcer disease.
- To identify potential risk factors for marginal ulcer development.
Main Methods:
- Prospective analysis of 201 consecutive laparoscopic gastric bypass procedures.
- Procedures utilized a linear stapled anastomosis and absorbable suture.
- Patient outcomes were monitored for complications, specifically marginal ulcer disease.
Main Results:
- The incidence of marginal ulcer disease was 3.5% (7 patients).
- Presentations included perforation (1 smoker), bleeding (3, requiring transfusion), and severe pain (3).
- Ulcerations were associated with Roux limb mucosa; all patients responded to proton pump inhibitors and sucralfate.
Conclusions:
- Marginal ulcers occurred in 3.5% of patients undergoing linear-stapled LGB.
- Distinct clinical presentations include bleeding, pain, and perforation.
- No preoperative risk factors predicted ulcer development; medical management proved effective.
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