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Updated: Jul 20, 2026
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A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery
Published on: January 18, 2018
[Effectiveness of analgesic techniques after breast surgery: a meta-analysis]
E Marret1, A Vigneau, A Salengro
1Département d'anesthésie-réanimation, hôpital Tenon, 4, rue de la Chine, 75020 Paris, France. emmanuel.marret@tnn.ap-hop-paris.fr
Annales Francaises D'Anesthesie Et De Reanimation
|August 24, 2006
Summary
Thoracic paravertebral block (TPVB) effectively reduces postoperative pain and nausea after breast surgery. Wound infiltration (WI) did not show significant benefits for pain or nausea in this meta-analysis.
Area of Science:
- Anesthesiology
- Surgical Pain Management
- Oncology
Context:
- Breast cancer surgery is a common procedure with significant postoperative pain and nausea.
- Effective pain management is crucial for patient recovery and satisfaction.
- Locoregional analgesic techniques offer targeted pain relief with potentially fewer systemic side effects.
Purpose:
- To compare the effectiveness of thoracic paravertebral block (TPVB) and wound infiltration (WI) for postoperative analgesia after breast surgery.
- To evaluate the impact of these techniques on pain scores and the incidence of postoperative nausea and vomiting (PONV).
Summary:
- A meta-analysis of nine randomized controlled trials (RCTs) evaluated single-injection TPVB and WI using local anesthetics in breast surgery patients.
- TPVB significantly reduced visual analog scale (VAS) pain scores at 6 and 12 hours post-surgery and decreased the incidence of PONV.
- Wound infiltration (WI) did not demonstrate significant reductions in postoperative pain or PONV.
Impact:
- Single-injection TPVB is a superior analgesic technique compared to WI for breast surgery, offering improved pain control and reduced PONV.
- Findings support the integration of TPVB into multimodal analgesia strategies for breast cancer patients.
- Optimized postoperative pain management can lead to faster recovery and improved patient outcomes.
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