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Updated: Jul 20, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
Paraneoplastic epidermolysis bullosa acquisita associated with multiple myeloma
Lida Radfar1, Mahnaz Fatahzadeh, Yasaman Shahamat
1Department of Oral Diagnostic Sciences, School of Dental Medicine, State University of New York at Buffalo, USA. lradfar@buffalo.edu
Abstract:
Epidermolysis bullosa acquisita is a rare acquired autoimmune subepidermal blistering disease that clinically resembles other vesiculobullous lesions such as pemphigus vulgaris and cicatricial pemphigoid. Multiple myeloma is the most common plasma cell malignant disorder characterized by a single clonal expansion and increased level of a single immunoglobulin. Epidermolysis bullosa acquisita has been reported with other systemic diseases such as lymphoma. In this case report, we present a patient with paraneoplastic epidermolysis bullosa acquisita associated with multiple myeloma.
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