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Updated: Jul 20, 2026

Gene Expression Analysis of Endothelial Cells Exposed to Shear Stress Using Multiple Parallel-plate Flow Chambers
Published on: October 21, 2018
Shear stress in cells generated by ultrasound
1Department of Physics, University of Vermont, Burlington, VT 05405, USA. Jun-ru@uvm.edu
Abstract:
An experimental study using a mason horn of 21.4 kHz indicated that the threshold shear stress for cell sonoporation was 12+/-4 Pa for ultrasound exposure time up to 7 min. Numerical calculations have shown that shear stress associated with microstreaming surrounding encapsulated bubbles may be large enough to generate sonoporation at 0.1 MPa of 1 or 2 MHz ultrasound.
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