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Updated: Jul 20, 2026

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
Is complete heart block after surgical closure of ventricular septum defects still an issue?
Henrik Ø Andersen1, Marc R de Leval, Victor T Tsang
1Department of Cardiothoracic Surgery, Rigshospitalet, Denmark. hoandersen@dadlnet.dk
Insights
Surgical closure of ventricular septal defects (VSD) can lead to complete heart block. This study identified anatomical factors to minimize this risk, suggesting a less than 1% incidence of iatrogenic heart block after VSD repair.
Area of Science:
- Cardiology
- Cardiac Surgery
- Pediatric Cardiology
Background:
- Complete heart block is a serious complication following surgical ventricular septal defect (VSD) closure.
- Identifying predisposing anatomical features is crucial for preventing surgically-induced heart block.
Purpose of the Study:
- To review the incidence of complete heart block after VSD closure.
- To identify anatomical factors predisposing to surgically-induced complete heart block.
- To provide anatomical guidelines to minimize this complication in future surgeries.
Main Methods:
- Retrospective study of patients undergoing VSD closure between 1976 and 2001.
- Data extracted for various VSD types including isolated VSD, tetralogy of Fallot, and aortic arch anomalies.
- Operative notes of patients with postoperative complete heart block were reviewed for anatomical reasons.
Main Results:
- 2,079 patients underwent VSD closure.
- Permanent complete heart block occurred in 0.7% of isolated VSD cases and 0.1% of tetralogy of Fallot cases.
- Four additional patients experienced postoperative complete heart block.
Conclusions:
- Iatrogenic complete heart block remains a risk after VSD closure due to biological variations or anatomical unawareness.
- The study emphasizes the importance of understanding atrioventricular conduction axis disposition.
- The overall risk of iatrogenic complete heart block after VSD closure is suggested to be less than 1%.
Background:
A serious complication after surgical closure of ventricular septal defect (VSD) is complete heart block. In this retrospective study, we reviewed the incidence of complete heart block after surgical closure of a VSD at Great Ormond Street Hospital from 1976 to 2001 to identify any particular anatomic features that still predisposed patients to surgically-induced complete heart block and to provide anatomic guidelines to avoid this in future.
Methods:
Data were extracted from our local database for patients having (1) isolated VSD or VSD in the setting of (2) tetralogy of Fallot with pulmonary stenosis or (3) tetralogy of Fallot with pulmonary atresia; (4) absent pulmonary valve syndrome; (5 and 6) coarctation or interruption of the aortic arch; and (7) subaortic fibrous shelf. We carefully reviewed the operative notes from all patients with postoperative complete heart block to discover any predisposing anatomical reasons to explain the complication.
Results:
Two thousand seventy-nine patients had a VSD closure. Permanent complete heart block developed in 7 of 996 patients (0.7%) with an isolated defect and in 1 of 847 patients (0.1%) with tetralogy of Fallot. Four more patients had postoperative complete heart block.
Conclusions:
Instances of iatrogenic complete heart block continue to occur after surgical VSD closure, either because of unexpected biological variations or because of unawareness of the disposition of the atrioventricular conduction axis in particular circumstances. This report emphasizes the latter aspect in details and suggests a risk of iatrogenic complete heart block of less than 1%.
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