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Updated: Jul 20, 2026

Bone Marrow Transplantation Procedures in Mice to Study Clonal Hematopoiesis
Published on: May 26, 2021
Dental management of pediatric patients undergoing hematopoietic stem cell transplant
Kenji Yamagata1, Kojiro Onizawa, Hiroshi Yoshida
1Division of Dentistry and Oral and Maxillofacial Surgery, Mito Saiseikai General Hospital, Ibaraki, Japan. y-kenji@md.tsukuba.ac.jp
Abstract:
This study was conducted to evaluate the outcomes of a dental management program the authors designed for pediatric patients receiving hematopoietic stem cell transplant (HSCT) for hematological malignancy. Thirty pediatric patients with hematological malignancies received dental management before HSCT. The outcomes of the dental management and any episode of odontogenic complication were retrospectively evaluated. The pretransplant oral examination showed one or more dental pathologies in 19 children (63.3%), and the remaining 11 patients showed no dental pathologies. Fifteen of the 19 children with dental pathologies received dental treatment, which included restoration, tooth-brushing instruction, scaling, endodontic therapy for permanent teeth, and extraction of primary teeth. No odontogenic infection occurred in any patient during the immunosuppressive period.
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