Related Experiment Video
Updated: Jul 20, 2026
05:12
Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
Published on: June 23, 2023
Comorbidity between substance use disorders and psychiatric conditions
1VA San Diego Healthcare System, San Diego, CA, USA. mschuckit@ucsd.edu
Addiction (Abingdon, England)
|August 26, 2006
Summary
Substance-induced mental disorders, such as psychoses, mood, and anxiety conditions, are prevalent and significantly contribute to comorbidity with substance use disorders. Recognizing these induced disorders is crucial for effective treatment.
Area of Science:
- Psychiatry
- Addiction Medicine
- Clinical Psychology
Background:
- Comorbidity between substance use disorders and psychiatric conditions is a significant clinical challenge.
- The existence and diagnostic criteria for substance-induced mental disorders require clarification.
Purpose of the Study:
- To review existing literature on the existence of substance-induced mental disorders.
- To explore the implications of these disorders for comorbidity and treatment.
Main Methods:
- Systematic literature review of English-language manuscripts.
- Focus on studies published since approximately 1970.
- Inclusion of research on comorbid psychiatric and substance use disorders.
Main Results:
- Evidence supports the existence of substance-induced mental disorders, particularly stimulant or cannabinoid-induced psychoses.
- Substance-induced mood and anxiety disorders are also supported by the findings.
- Methodological variations in studies impact specific results.
Conclusions:
- Substance-induced disorders are sufficiently prevalent to significantly impact comorbidity rates.
- Recognition of these disorders has critical implications for patient treatment strategies.
- The heterogeneity of comorbidity in this field is highlighted.
Related Concept Videos
01:24Substance Use Disorders Affecting Sleep
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Understanding the concepts of physical dependence,...
01:30Stress and Mental Health
Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
Individuals with depression often experience challenges in both their personal and professional...
01:27Diagnostic and Statistical Manual of Mental Disorders (DSM)
The Diagnostic and Statistical Manual of Mental Disorders (DSM) serves as the primary classification system for mental health disorders, providing standardized diagnostic criteria for clinicians and researchers. First published by the American Psychiatric Association (APA) in 1952, the DSM has undergone several revisions to reflect evolving psychiatric understanding. The fifth edition, DSM-5, released in 2013, introduced key updates that expanded diagnostic categories and modified diagnostic...
01:15Drug Abuse and Addiction: Pharmacological Phenomena
Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not necessarily...
01:17Drug Dependence
Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting in various enjoyable experiences. However, this can result in drug dependency, a condition marked by continuous drug use despite potential negative consequences. Drug dependency primarily falls into two categories: psychological and physical dependence. Psychological dependence occurs when the pleasurable feelings induced by the drug...
01:27CNS Depressants: Alcohol and Nicotine
Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...