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Updated: Jul 20, 2026

A Mouse Ear Model for Allergic Contact Dermatitis Evaluation
Published on: March 24, 2023
Occupational peri-ocular contact dermatitis due to sensitization against black rubber components of a microscope
D I M Kuijpers1, F Hillen, J A Frank
1Department of Dermatology, University Hospital Maastricht, Masstricht, the Netherlands. dku@sder.azm.nl
Abstract:
A 24-year-old female working in the Department of Pathology of a University Hospital developed an acute peri-ocular eczema clearly being related to her daily work at the microscope. Patch testing revealed delayed type hypersensitivity against the black rubber mix, N-isopropyl-N'-phenyl paraphenylenediamine, N-cyclohexyl-N'-phenyl paraphenylenediamine and the rubber ring situated on the ocular of the respective microscope. This is the first report, to our knowledge, on peri-orbital allergic contact eczema because of sensitization with rubber components of a microscope.
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