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Updated: Jul 20, 2026

Micro-Colony Forming Unit Assay for Efficacy Evaluation of Vaccines Against Tuberculosis
Published on: July 28, 2023
Comparison of three diagnostic detection methods for tuberculosis in French cattle
D Watrelot-Virieux1, E Drevon-Gaillot, Y Toussaint
1Ecole Nationale Vétérinaire de Lyon, Département de Pathologie, 1, Avenue Bourgelat. B.P. 83, 69280 Marcy L'etoile, France. d.watrelot@vet-lyon.fr
Abstract:
Three additional techniques (Ziehl-Neelsen, auramine O/rhodamine and immunostaining using polyclonal anti-Mycobacterium bovis) to hematoxylin-eosin histopathology were evaluated for bovine tuberculosis diagnosis on 39 samples from several slaughterhouses. The immunohistochemichal technique was more sensitive and could detect a greater number of positive cattle. It has about the same sensibility as the bacteriology but it was faster.
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