Strabismus in craniosynostosis
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Updated: Jul 20, 2026

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
1Alfred I. duPont Hospital for Children, Ophthalmology, Wilmington, Delaware 19803, USA. slehman@nemours.org
Purpose Of Review:
To present peer-reviewed articles related to strabismus in craniosynostosis.
Recent Findings:
Improved neurosurgical treatment has resulted in amblyopia replacing optic atrophy as the main cause of visual impairment in Apert's and Crouzon syndromes. Patients with nonsyndromic craniosynostosis have an increased incidence of significant refractive error and horizontal strabismus similar to syndromic craniosynostosis. Imaging of the orbit and extraocular muscles continues to be recommended as helpful for presurgical planning. Surgical techniques continue to be explored in order to improve outcomes for craniosynostosis patients.
Summary:
Attention to diagnosis and treatment of amblyopia and strabismus is necessary to preserve vision in craniosynostosis patients. Orbital imaging may aid in planning for these patients whose strabismus surgery remains a challenge.
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