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Updated: Jul 20, 2026
A Uniform Shear Assay for Human Platelet and Cell Surface Receptors via Cone-plate Viscometry
Published on: June 5, 2019
A novel agglutination test for antigen-specific detection of platelet antibodies
Oliver Meyer1, Ashraf Agaylan, Hans-Hubert Borchert
1Charité, Institute of Transfusion Medicine, Augustenburger Platz 1, Berlin, Germany.
Abstract:
A simple and rapid antigen-specific assay for the identification antibodies to platelets is lacking, yet. Red-dyed polystyrene microbeads were coated with monoclonal antibodies to various platelet glycoprotein complexes, and used for the detection of platelet autoantibodies and alloantibodies. The results were largely identical with those obtained by monoclonal antibody-specific immobilization of platelet antigen assay (MAIPA). The new test is reliable yet less complex and time-consuming than the currently available assays, and it can be implemented in any routine laboratory.
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