Bisindole alkaloids from myxomycetes Arcyria denudata and Arcyria obvelata
Kazuaki Kamata1, Tomoko Suetsugu, Yukinori Yamamoto
1Graduate School of Pharmaceutical Sciences, Chiba University, Chiba 263-8522, Japan.
Abstract:
A new bisindole sulfate (1) and arcyroxocin B (2) were isolated from wild fruiting bodies of Arcyria denudate, along with three known bisindoles (4-6). Dihydroarcyriacyanin A (3) was obtained from wild fruiting bodies of Arcyria obvelata, along with a known bisindole (7). The structures of these compounds were elucidated on the basis of spectroscopic data, and this is the first report of full characterizations of arcyroxocin B (2) and dihydroarcyriacyanin A (3). Compounds 2, 3, and 6 showed cytotoxicity against Jurkat cells.
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