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In Vitro Modeling of Down Syndrome Neurogenesis Using Human-Induced Pluripotent Stem Cells
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The challenge of Down syndrome

Stylianos E Antonarakis1, Charles J Epstein

  • 1Department of Genetic Medicine and Development, University of Geneva Medical School, University Hospitals of Geneva, 1 rue Michel-Servet, 1211 Geneva, Switzerland.

Trends in Molecular Medicine
|August 29, 2006
PubMed
Summary

Recent advances in genetics and neuroscience offer hope for understanding Down syndrome (DS) pathogenesis. This research aims to translate findings into improved prevention and treatment strategies for individuals with DS.

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