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Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
[The TomoTherapy Hi.Art System for sophisticated IMRT and IGRT with helical delivery: Recent developments and
1Unité d'imagerie moléculaire et radiothérapie expérimentale (IMRE), université catholique de Louvain, 10/4752, avenue Hippocrate, 1200 Bruxelles, Belgique. milan.tomsej@imre.ucl.ac.be
Abstract:
The advent of 3D conformal radiotherapy and intensity modulated radiation therapy (IMRT) make possible the dose optimization to complex target volumes close to sane organs at risk. IMRT's introduction of numerous small radiation fields inherently increases delivery inaccuracies. As a consequence, the use of IMRT without precise localization of the tumor and sensitive structures, at both the planning and delivery stages, and the absence of continuous verification represent the most significant challenges to the implementation of IMRT in routine clinical use. Intensity modulated (or not) conformal radiotherapy delivery requires better precision in the definition of treatment volume, frequently if necessary. Helical tomotherapy has been designed to use CT imaging technology to plan, deliver, and verify that the delivery has been carried out as planned. The image-guided and intensity modulations processes of helical tomotherapy that enable this goal are described.
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