Topical photodynamic therapy: an introduction for nurses

Area of Science:

• Dermatology
• Oncology
• Photomedicine

Background:

• Non-melanoma skin cancers are the most prevalent cancers in the UK, with significant under-reporting.
• Cancer registries exclude pre-cancerous skin lesions, meaning treated numbers far exceed reported cancer cases.
• Topical photodynamic therapy (PDT) is an established, effective treatment for pre-malignant and malignant non-pigmented skin cancers.

Purpose of the Study:

• To introduce nurses to topical photodynamic therapy (PDT).
• To provide information for nurses involved in establishing PDT services.
• To explain the mechanism and application of PDT in treating skin cancers.

Main Methods:

• PDT involves a two-step process: application of a photosensitizing agent followed by light exposure.
• The treatment is non-invasive and can be administered in a clinical setting.
• PDT targets and eliminates tumour cells while sparing surrounding healthy tissue.

Main Results:

• PDT effectively eliminates pre-malignant and malignant skin lesions.
• The treatment demonstrates selectivity, leaving healthy skin unharmed.
• PDT is a viable option for nurses to administer in clinical practice.

Conclusions:

• Topical photodynamic therapy is a valuable, non-invasive treatment modality for non-melanoma skin conditions.
• Nurses can play a key role in the implementation and delivery of PDT services.
• Further understanding of PDT is essential for healthcare professionals managing skin cancer patients.