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Updated: Jul 20, 2026
09:11
Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy
Published on: April 9, 2019
[Power Doppler Imaging and prostate cancer: optional or necessary technique?]
J L Sauvain1, P Palascak, N Nader
1Centre d'Imagerie Médicale, 6 passage Jules Didier, 70000 Vesoul, France. JLFSAUVAIN@aol.com
Journal De Radiologie
|August 29, 2006
Summary
Power Doppler sonography (PDS) improves prostate cancer detection and staging. This imaging technique helps identify aggressive features and optimize biopsy core selection, enhancing patient management.
Area of Science:
- Urology
- Medical Imaging
- Oncology
Background:
- Elevated prostate-specific antigen (PSA) levels necessitate accurate prostate cancer diagnosis.
- Power Doppler sonography (PDS) offers potential advantages in visualizing prostate abnormalities.
Purpose of the Study:
- To assess the utility of PDS in patients with PSA > 3.5 ng/ml.
- To evaluate PDS for improving biopsy core management and cancer staging.
Main Methods:
- 579 patients with PSA > 3.5 ng/ml underwent initial sextant biopsies.
- PDS was performed prior to biopsy indication.
- Additional Doppler-guided biopsies were performed for persistent elevated PSA.
Main Results:
- PDS detected vascular anomalies corresponding to 260 cancers; 39 were false negatives.
- An abnormal Doppler signal predicted an 83% risk of positive additional biopsies.
- Vascular patterns correlated with Gleason score and extraprostatic extension.
Conclusions:
- PDS aids in evaluating prostate cancer aggressiveness.
- The technique optimizes the selection of diagnostically useful biopsy cores.
- PDS enhances the management and staging of prostate cancer.
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