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[Growth and body composition in children with type 1 diabetes mellitus]

Maria F V M Paulino1, Sofia H V de Lemos-Marini, Gil Guerra-Júnior

  • 1Hospital de Clínicas, Faculdade de Ciências Médicas, Universidade Estadual de Campinas (UNICAMP), Rua Antonio Augusto de Almeida 182, 13084-755 Campinas, SP. rspaulino@hotmail.com

Arquivos Brasileiros De Endocrinologia E Metabologia
|August 29, 2006
PubMed

Insights

Pre-pubertal children with diabetes showed reduced height standard deviation scores (SDS) and increased arm fat compared to controls. Diabetes duration influenced height SDS reduction in these young patients.

Area of Science:

  • Pediatric Endocrinology
  • Metabolic Disorders
  • Growth and Development

Background:

  • Type 1 diabetes is a chronic condition affecting children.
  • Understanding the impact of diabetes on growth and body composition is crucial for management.
  • Pre-pubertal children with diabetes may experience altered growth patterns.

Purpose of the Study:

  • To assess growth and body composition in pre-pubertal diabetic children.
  • To investigate the influence of diabetes duration, age of onset, sex, insulin needs, and glycemic control (HbA1c) on these parameters.

Main Methods:

  • A cohort of 59 pre-pubertal diabetic children and 67 healthy controls were studied.
  • Measurements included weight, height, BMI, arm circumference, skinfolds, fat mass, and muscle area, all converted to standard deviation scores (SDS).

Main Results:

  • Diabetic children had significantly lower mean height SDS (-0.13) compared to controls (0.28).
  • Height SDS significantly decreased over time, correlated with diabetes duration.
  • Arm fat SDS was significantly higher in diabetic children compared to controls.

Conclusions:

  • Pre-pubertal diabetic children exhibit reduced height SDS and increased arm fat compared to controls.
  • The duration of diabetes is a significant factor in the observed decrease in height SDS.
  • Despite differences, the children's statures remained within population standards.
Abstract

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